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For this, we analysed the transcriptomes of primary hepatocytes at the time of isolation and their matching h-HepOrgs under DM to identify the specific gene signatures of each patient

Morphological characterization of MDMOC The morphology and EDS of the MDMOC were analyzed using an SEM (Quanta 400 F, FEI, USA)

Lastly, the models were trained and tested on American and Caucasian-skewed cohorts, and future studies should assess the generalizability of the findings in more ethnically and geographically diverse populations